Authors: Sabin JE, Mazor K, Meterko V, Goff SL, Platt R
Title: Comparing drug effectiveness at health plans: the ethics of cluster randomized trials.
Journal: Hastings Cent Rep 38(5):39-48
Date: 2008 Sep-Oct
Abstract: "Cluster randomized trials," in which groups of patients are randomly assigned to different therapeutic interventions, provide a powerful way of evaluating drugs. CRTs have not been widely used, in good part because of concerns about whether patients must give informed consent to participate in them. A better understanding of how CRTs fit into clinical practice resolves the concerns.
Last Updated: 02 Mar 2015