Tools to Improve Use of Patient-Reported Outcomes in Clinical Trials: Introducing the PROTEUS Toolbox
Purpose
This session provides an opportunity for NIH Program Directors, Research Support Staff, and Pre- and Post-Doctoral Trainees to learn more about the recently completed PROTEUS (Patient-Reported Outcomes Tools: Engaging Users & Stakeholders) Toolbox.
PROTEUS brings together a set of resources to enhance the rigor and utility of PROs endpoints in clinical trials. This webinar highlights how PROTEUS can improve the collection, analysis, interpretation, and applicability of patient-reported outcomes (PROs) in trials.
In this webinar, speakers and discussants
- Provide an overview of PROTEUS, including its goals, methods, and future directions
- Describe the methodologic tools available within PROTEUS, including standards, guidance documents, checklists, and training videos, and describe their use in defining PRO-based trial endpoints, developing study protocols, and analyzing, reporting, and displaying PRO data
- Highlight ways NIH staff and trainees can implement PROTEUS resources when consulting with grant applicants, reviewing protocols or manuscripts, or planning training activities
Pre-Webinar Resources
- Calvert M, Kyte D, Mercieca-Bebber R, Slade A, et al. Guidelines for inclusion of patient-reported outcomes in clinical trial protocols: The SPIRIT-PRO extension. JAMA. 2018; 319:483-494.
- Coens C, Pe M, Dueck AC, et al. International standards for the analysis of quality of life and patient reported outcomes endpoints in cancer randomized controlled trials: Recommendations based on critical reviews of the literature and international multi-expert, multi-stakeholder collaborative process. Lancet Oncology. 2020;21:e83-96.
- Reeve BB, Wyrwich KW, Wu AW, et al. ISOQOL recommends minimum standards for patient-reported outcome measures used in patient-centered outcomes and comparative effectiveness research. Quality of Life Research. 2013;22:1889-1905.
For more information visit our website.
Intended Audience
NIH Program Directors, Pre- and Post-Doctoral Trainees at NIH, other NIH Staff.
Presenters
![Claire Snyder](/images/webinars/snyder.jpg)
Claire Snyder, MHS, PhD
Professor
Johns Hopkins University School of Medicine
![Michael Brundage](/images/webinars/brundagem.jpg)
Michael Brundage, MD, MSc, FRCP(C)
Director, Division of Cancer Care and Epidemiology
Queen's Cancer Research Institute
Discussants
![Paul B. Jacobsen](/images/webinars/jacobsen.jpg)
Paul B. Jacobsen, PhD
Healthcare Delivery Research Program
Division of Cancer Control and Population Sciences: NCI
![Diane St. Germain](/images/webinars/stgermaind.jpg)
Diane St. Germain, RN, MS
Community Oncology and Prevention Trials Research Group
Division of Cancer Prevention: NCI
![Sandra A. Mitchell](/images/webinars/mitchell.jpg)
Sandra A. Mitchell, PhD, CRNP
Outcomes Research Branch
Division of Cancer Control and Population Sciences: NCI
This webinar will be archived on the HDRP Events webpage.