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Tools to Improve Use of Patient-Reported Outcomes in Clinical Trials: Introducing the PROTEUS Toolbox
Purpose
This session provides an opportunity for NIH Program Directors, Research Support Staff, and Pre- and Post-Doctoral Trainees to learn more about the recently completed PROTEUS (Patient-Reported Outcomes Tools: Engaging Users & Stakeholders)
Toolbox.
PROTEUS brings together a set of resources to enhance the rigor and utility of PROs endpoints in clinical trials. This webinar highlights how PROTEUS can improve the collection, analysis, interpretation, and applicability of patient-reported outcomes (PROs) in trials.
In this webinar, speakers and discussants
- Provide an overview of PROTEUS, including its goals, methods, and future directions
- Describe the methodologic tools available within PROTEUS, including standards, guidance documents, checklists, and training videos, and describe their use in defining PRO-based trial endpoints, developing study protocols, and analyzing, reporting, and displaying PRO data
- Highlight ways NIH staff and trainees can implement PROTEUS resources when consulting with grant applicants, reviewing protocols or manuscripts, or planning training activities
Pre-Webinar Resources
- Calvert M, Kyte D, Mercieca-Bebber R, Slade A, et al. Guidelines for inclusion of patient-reported outcomes in clinical trial protocols: The SPIRIT-PRO extension. JAMA. 2018; 319:483-494.
- Coens C, Pe M, Dueck AC, et al. International standards for the analysis of quality of life and patient reported outcomes endpoints in cancer randomized controlled trials: Recommendations based on critical reviews of the literature and international multi-expert, multi-stakeholder collaborative process. Lancet Oncology. 2020;21:e83-96.
- Reeve BB, Wyrwich KW, Wu AW, et al. ISOQOL recommends minimum standards for patient-reported outcome measures used in patient-centered outcomes and comparative effectiveness research. Quality of Life Research. 2013;22:1889-1905.
For more information visit our website.
Intended Audience
NIH Program Directors, Pre- and Post-Doctoral Trainees at NIH, other NIH Staff.
Presenters
Claire Snyder, MHS, PhD
Professor
Johns Hopkins University School of Medicine
Michael Brundage, MD, MSc, FRCP(C)
Director, Division of Cancer Care and Epidemiology
Queen's Cancer Research Institute
Discussants
Paul B. Jacobsen, PhD
Healthcare Delivery Research Program
Division of Cancer Control and Population Sciences: NCI
Diane St. Germain, RN, MS
Community Oncology and Prevention Trials Research Group
Division of Cancer Prevention: NCI
Sandra A. Mitchell, PhD, CRNP
Outcomes Research Branch
Division of Cancer Control and Population Sciences: NCI
This webinar will be archived on the HDRP Events webpage.