Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE®)

This site was designed to provide you with information about PRO-CTCAE®, a patient-reported outcome measurement system developed by the National Cancer Institute to capture symptomatic adverse events in patients on cancer clinical trials. The availability of PRO-CTCAE in more than 60 validated languages supports the inclusion of culturally and linguistically diverse populations in cancer clinical trials and addresses language-related barriers to the equitable participation of underrepresented groups.

More About PRO-CTCAE
PRO-CTCAE logo

Announcements

  • The Ped-PRO-CTCAE module capturing symptomatic adverse events from children and their caregiver proxies is now available in Spanish following validation in Mexico and Spain.
  • Ped-PRO-CTCAE module English language version has been updated and is now considered 'Universal' having been validated in Canada, UK and Australia. Consult release notes for details and to view corresponding changes to the Italian and Simplified Chinese item libraries.

Measurement System

The National Cancer Institute’s PRO-CTCAE Measurement System was developed to capture symptomatic toxicity by self-report in adults, children and adolescents participating in cancer clinical trials.

Instruments & Form Builder

Download the full instruments, preview the item libraries using the Quick Guides, or use our Form Builders to produce a custom survey in any available language for your study.

Frequently Asked Questions and Resources

If you have questions about the PRO-CTCAE Measurement System, please read the FAQ section.

Release Notes

Release notes highlight any changes, updates or corrections made to PRO-CTCAE Item Libraries.

Resources

Last Updated: 04 Sep, 2024