Language Translation: Methods and Certificates
- Methods used to translate and linguistically validate PRO-CTCAE follow the Principles of Good Translation and Cultural Adaptation Practice as articulated by ISPOR in 2005.
- These methods include:
- development of item definitions;
- dual forward translation with reconciliation, dual back translation, back translation review and harmonization;
- review by a bilingual oncology clinician (physician or nurse) to verify terminology;
- final proofing by another independent bilingual oncology clinician, including diacritics; and
- cognitive testing with a diverse sample of cancer patients who are receiving active cancer treatment or who have recently completed active treatment.
- This approach is designed to yield translated versions of PRO-CTCAE that are conceptually equivalent to the English version, and readily understood by the target population.
- The PRO-CTCAE Instrument is currently available in seven languages: English, Spanish, German, Italian, Danish, Japanese, and Korean. Additional translations are in development (including Chinese, Czech, Dutch-Flemish, French, Greek, Hungarian, Polish, Portuguese, Russian, and Swedish), and will be posted upon completion.
- To assure standardized translations, users are not permitted to translate PRO-CTCAE without a prior written agreement with the National Cancer Institute.
- NCI does not recommend using translations that have not been evaluated through cognitive interviewing.
- To assure consistency, all translations should be obtained directly from NCI.
- Each translated version includes certification of the procedures used to assure conceptual equivalence.
Certificates of Translation
- Certificate of Translation into Danish (PDF, 135 KB)
- Certificate of Translation into German (PDF, 136 KB)
- Certificate of Translation into Italian (PDF, 118 KB)
- Certificate of Translation into Japanese (PDF, 151 KB)
- Certificate of Translation into Korean (PDF, 110 KB)
- Certificate of Translation into Spanish (PDF, 524 KB)
Last Updated: 16 Oct 2017