Correspondence Between PRO-CTCAE and CTCAE Terminologies

PRO-CTCAE Symptom Terms and Corresponding CTCAE Terms

Oral

PRO-CTCAE Symptom Term Corresponding CTCAE Version 5.0External Web Site Policy Term
Dry mouth Dry mouth
Difficulty swallowing Dysphagia
Mouth/throat sores Mucositis oral
Cracking at the corners of the mouth (cheilosis/cheilitis) Cheilitis
Voice quality changes Voice alteration
Hoarseness Hoarseness

Gastrointestinal

PRO-CTCAE Symptom Term Corresponding CTCAE Version 5.0External Web Site Policy Term
Taste changes Dysgeusia
Decreased appetite Anorexia
Nausea Nausea
Vomiting Vomiting
Heartburn Dyspepsia
Gas Flatulence
Bloating Bloating
Hiccups Hiccups
Constipation Constipation
Diarrhea Diarrhea
Abdominal pain Abdominal pain
Fecal incontinence Fecal incontinence

Respiratory

PRO-CTCAE Symptom Term Corresponding CTCAE Version 5.0External Web Site Policy Term
Shortness of breath Dyspnea
Cough Cough
Wheezing Wheezing

Cardio/Circulatory

PRO-CTCAE Symptom Term Corresponding CTCAE Version 5.0External Web Site Policy Term
Swelling Edema limbs
Heart palpitations Palpitations

Cutaneous

PRO-CTCAE Symptom Term Corresponding CTCAE Version 5.0External Web Site Policy Term
Rash Rash maculo-papular
Skin dryness Dry skin
Acne Rash acneiform
Hair loss Alopecia
Itching Pruritus
Hives Urticaria
Hand-foot syndrome Palmar-plantar erythrodysesthesia syndrome
Nail loss Nail loss
Nail ridging Nail ridging
Nail discoloration Nail discoloration
Sensitivity to sunlight Photosensitivity
Bed/pressure sores Skin ulceration
Radiation skin reaction Dermatitis radiation
Skin darkening Skin hyperpigmentation
Stretch marks Skin and subcutaneous tissue disorders – Other, specifiy: (Striae)

Neurological

PRO-CTCAE Symptom Term Corresponding CTCAE Version 5.0External Web Site Policy Term
Numbness & tingling Peripheral sensory neuropathy
Dizziness Dizziness

Visual/Perceptual

PRO-CTCAE Symptom Term Corresponding CTCAE Version 5.0External Web Site Policy Term
Blurred vision Blurred vision
Flashing lights Flashing lights
Visual floaters Floaters
Watery eyes Watering eyes
Ringing in ears Tinnitus

Attention/Memory

PRO-CTCAE Symptom Term Corresponding CTCAE Version 5.0External Web Site Policy Term
Concentration Concentration impairment
Memory Memory impairment

Pain

PRO-CTCAE Symptom Term Corresponding CTCAE Version 5.0External Web Site Policy Term
General Pain Pain
Headache Headache
Muscle pain Myalgia
Joint pain Arthralgia

Sleep/Wake

PRO-CTCAE Symptom Term Corresponding CTCAE Version 5.0External Web Site Policy Term
Insomnia Insomnia
Fatigue Fatigue

Mood

PRO-CTCAE Symptom Term Corresponding CTCAE Version 5.0External Web Site Policy Term
Anxious Anxiety
Discouraged Depression
Sad Depression

Genitourinary

PRO-CTCAE Symptom Term Corresponding CTCAE Version 5.0External Web Site Policy Term
Irregular periods/vaginal bleeding Irregular menstruation
Missed expected menstrual period Irregular menstruation
Vaginal discharge Vaginal discharge
Vaginal dryness Vaginal dryness
Painful urination Urinary tract pain
Urinary urgenc Urinary urgency
Urinary frequency Urinary frequency
Change in usual urine color Urine discoloration
Urinary incontinence Urinary incontinence

Sexual

PRO-CTCAE Symptom Term Corresponding CTCAE Version 5.0External Web Site Policy Term
Achieve and maintain erection Erectile dysfunction
Ejaculation Ejaculation disorder
Decreased libido Libido decreased
Delayed orgasm Delayed orgasm
Unable to have orgasm Anorgasmia
Pain w/sexual intercourse Dyspareunia

Miscellaneous

PRO-CTCAE Symptom Term Corresponding CTCAE Version 5.0External Web Site Policy Term
Breast swelling and tenderness Gynecomastia (males)
Breast pain (women)
Bruising Bruising
Chills Chills
Increased sweating Hyperhidrosis
Decreased sweating Hypohidrosis
Hot flashes Hot flashes
Nosebleed Epistaxis
Pain and swelling at injection site Injection site reaction
Body odor Body odor

Ped-PRO-CTCAE Symptom Terms and Corresponding CTCAE Terms

Oral

PRO-CTCAE Symptom Term (Pediatric Module) Corresponding CTCAE Version 5.0External Web Site Policy Term
Dry mouth Dry mouth
Difficulty swallowing Dysphagia
Mouth/throat sores Mucositis oral
Voice quality changes Voice alteration
Hoarseness Hoarseness
Sore throat Sore throat

Gastrointestinal

PRO-CTCAE Symptom Term (Pediatric Module) Corresponding CTCAE Version 5.0External Web Site Policy Term
Taste changes Dysgeusia
Decreased appetite Anorexia
Nausea Nausea
Vomiting Vomiting
Heartburn Dyspepsia
Gas Flatulence
Bloating Bloating
Hiccups Hiccups
Constipation Constipation
Diarrhea Diarrhea
Abdominal pain Abdominal pain
Fecal incontinence Fecal incontinence

Respiratory

PRO-CTCAE Symptom Term (Pediatric Module) Corresponding CTCAE Version 5.0External Web Site Policy Term
Shortness of breath Dyspnea
Cough Cough
Wheezing Wheezing
Sneezing Sneezing

Cardio/Circulatory

PRO-CTCAE Symptom Term (Pediatric Module) Corresponding CTCAE Version 5.0External Web Site Policy Term
Swelling Edema limbs
Heart palpitations Palpitations

Cutaneous

PRO-CTCAE Symptom Term (Pediatric Module) Corresponding CTCAE Version 5.0External Web Site Policy Term
Skin dryness Dry skin
Acne Rash acneiform
Hair loss Alopecia
Itching Pruritus
Hives Urticaria
Sensitivity to sunlight Photosensitivity
Skin ulceration Skin ulceration

Neurological

PRO-CTCAE Symptom Term (Pediatric Module) Corresponding CTCAE Version 5.0External Web Site Policy Term
Numbness & tingling Peripheral sensory neuropathy
Dizziness Dizziness

Visual/Perceptual

PRO-CTCAE Symptom Term (Pediatric Module) Corresponding CTCAE Version 5.0External Web Site Policy Term
Blurred vision Blurred vision
Flashing lights Flashing lights
Watery eyes Watering eyes
Ringing in ears Tinnitus
Dry eyes Dry eye

Attention/Memory

PRO-CTCAE Symptom Term (Pediatric Module) Corresponding CTCAE Version 5.0External Web Site Policy Term
Concentration Concentration impairment
Memory Memory impairment

Pain

PRO-CTCAE Symptom Term (Pediatric Module) Corresponding CTCAE Version 5.0External Web Site Policy Term
General Pain Pain
Headache Headache
Muscle pain Myalgia
Joint pain Arthralgia

Sleep/Wake

PRO-CTCAE Symptom Term (Pediatric Module) Corresponding CTCAE Version 5.0External Web Site Policy Term
Insomnia Insomnia
Fatigue Fatigue

Mood

PRO-CTCAE Symptom Term (Pediatric Module) Corresponding CTCAE Version 5.0External Web Site Policy Term
Anxious Anxiety
Sad Depression
Suicidal ideation Suicidal ideation

Genitourinary

PRO-CTCAE Symptom Term (Pediatric Module) Corresponding CTCAE Version 5.0External Web Site Policy Term
Painful urination Urinary tract pain
Urinary urgenc Urinary urgency
Urinary frequency Urinary frequency
Change in usual urine color Urine discoloration
Urinary incontinence Urinary incontinence

Miscellaneous

PRO-CTCAE Symptom Term (Pediatric Module) Corresponding CTCAE Version 5.0External Web Site Policy Term
Bruising Bruising
Chills Chills
Increased sweating Hyperhidrosis
Hot flashes Hot flashes
Nosebleed Epistaxis
Falls Fall
Muscle weakness Generalized muscle weakness
Restlessness Akathisia
Last Updated: 15 Feb, 2024